I've labelled this "vacation photo" as separate from "travel"; the latter being a trip specifically to take high quality photos.
On a vacation trip, moving rather too quickly from place to place (either within a city or between locations), the time of day, photo opportunities and allowed time to stop are limited therefore it may be appropriate to pre-set camera controls so as not to miss a good shot.
In these circumstances would it be better to go with an auto ISO, aperture priority, matrix-weighted exposure or some other combination of control? My camera is a Nikon P7700; so an "advanced" point-and-shoot.