Hi Mariko,
I note from the EXIF data that it was shot on a Nikon D90 at 21mm using the 18 - 105mm kit lens.
We are assuming this is an uncropped in post processing, are we correct?
The EXIF appears to support this assumption, PP being simple, using LightRoom 4.4 from a nef RAW file.
I agree with the view that the entire left hand side appears to be very soft and mis-shapen - it may be a silly question (forgive me), but have you checked the front element (or filter) is clean?
i.e. it is not suffering a large smeary palm or finger print where you tried to catch it
Colin is correct about needing to be systematic diagnosing problems.
Can you at least stand "square on" to a brick wall and shoot that?
So everything is at the same distance from the camera.
Cheers,