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Originally Posted by
William W
Good point.
(REF the CPN Member's Data Sheets) - "ERR 80" is an 'electrical problem' or 'image problem'.
The fact that ERR 80 happened to you after you were carrying the camera one handed and removed the lens with the camera powered ON, certainly could have been the initiating cause of ERR80, but my best guess, based on experience, and my library of EOS Data and Reference material, is probably more likely to have been an electrical short across the lens's / camera's contacts via moisture or a contaminate creeping into the little gap between lens and camera which was conductive and shorted as you removed the lens, rather than an alignment problem with your lens and camera.
ERR80 can also be initiated because of an alignment problem - but there also needs to be a conductive material to short the contacts, or the contacts to be damaged in some way so that they short, in which case it would be more likely that you'd get the problem all the time with that particular lens & camera combination.
I concur with your good advice to remove the lens. Also it would be good to clean and dry those electrical contacts.
WW
BTW - 'guilty' I rarely turn my cameras OFF to change lenses.