Originally Posted by
Mike Buckley
Allan's explanation makes sense to me assuming ColorMunki works the same in that regard as Spyder. Once you use ColorMunki to calibrate the monitor, one of the last steps if not the last step in the ColorMunki process is to save the profile. It should automatically save it in the proper location on your computer without you having to know where it is saved. Just continue using your computer as usual.
When the time comes that you need to reboot your computer, the operating system should automatically find the saved profile and load it. If ColorMunki's software works the same as Spyder's software, a message will be automatically displayed indicating that the profile has been successfully loaded. If you're closely watching your monitor at the time it is loaded, any change the profile makes to your system will be noticeable unless the change is so slight that you can't see the difference between the uncalibrated monitor and the calibrated monitor.
Hope that helps! As a reminder, I use Spyder rather than ColorMunki. I posted this information only so you wouldn't have to wait longer than you already have for a helpful response. It would be ideal if a ColorMunki user would confirm this information.