Don't worry about it as it can happen on occasion and when I get a weird result I do like you did and just re-run the profiling / calibration process. I will also compare my new profile and old profile just to make sure that nothing strange has happened.
The monthly profiling is a hold-over from the days of CRT screens that did lose calibration fairly quickly. Modern LCD screens are incredibly stable and profiling and calibrating even once a year seems to be overkill. I generally do this and at the end of the day I often wonder why I bothered because nothing has changed. One knowledgeable person told me that the only time one can expect to see significant changes in screen output is just before the screen dies...